This verdict comes after just few hours of listen. I will be comparing it to straight usb input on my Topping e70 velvet dac. I got the po100 connected to pc with iFis iDefender and iPurifier 3 and powered with iPower X 5v then coax to mentioned dac.
Music plays now a lot more effortless, more fluid, all instruments and especially voices are now cleaner and more present.
Definitely worth it. Peace :)